Hardy-Weinberg Activity


Objective: For each trait surveyed (except for colorblindness), to determine the number of individuals expected to exhibit the dominant phenotype and the number and individuals expected to exhibit the recessive phenotype.


Directions:

1. Make sure you have:
a. A calculator 
b. Hard copies of data from this Genetics Project 
c. Hard copies of tables 1 and 2
2.2

For each trait surveyed (except for colorblindness), record the value of q2 in Table 1.

For assistance with finding q2, click here.
3.

For each trait surveyed (except for colorblindness), use the Hardy-Weinberg Equilibrium Equation (shown below) to calculate the values of q, p, p2 and 2pq. Click here for assistance.

 

p2 + 2pq +  q2 = 1

 
4. Record the values in Table 1.
   
5. Fill in row one of Table 2 (t, the total number of individuals surveyed for each trait) using the information from the printed copy of the genetics project data.
   
6. For each trait, use the values from Table 1 to calculate the expected number of individuals who show the:
 
a. dominant phenotype  (p2 + 2pq) x Total Number of Individuals Surveyed)
b. recessive phenotype (q2) x Total Number of Individuals Surveyed)
 
7. Record your answers in Table 2. (When completed, this table will serve as the starting point for the Chi Squared Analysis Activity.)

 


Resources:

Hardy-Weinberg Equilibrium Model - A must-read to see the math involved and a sample problem

Hardy-Weinberg Equilibrium - The Hardy-Weinberg Equilibrium made easy

Human Genetics Lab - Hardy-Weinberg and the Chi Square test

Population Genetics - Good Hardy-Weinberg example